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Loratadine

     

 

DESCRIPTION

Loratadine is a white to off-white powder not soluble in water, but very soluble in acetone, alcohol, and chloroform. It has a molecular weight of 382.89, and empirical formula of C22H23ClN2O2; its chemical name is ethyl4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1- piperidinecarboxylate and has the following structural formula:

Lorat

Claritin tablets contain 10 mg micronized loratadine, an antihistamine, to be administered orally. They also contain the following inactive ingredients: Corn starch, lactose, and magnesium stearate.

Claritin syrup contains 1 mg/ml micronized loratadine, an antihistamine, to be administered orally. It also contains the following inactive ingredients: Citric acid, artificial flavor, glycerin, propylene glycol, sodium benzoate, sugar, and water. The pH is between 2.5 and 3.1.

 

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