NILANDRON®
(nilutamide)
Tablets
DESCRIPTION
NILANDRON™ tablets contain nilutamide, a nonsteroidal, orally active antiandrogen having the chemical name 5,5-dimethyl 3-[4-nitro 3-(trifluoromethyl) phenyl] 2,4-imidazolidinedione with the following structural formula:
Nilutamide is a microcrystalline, white to practically white powder with a molecular weight of 317.25. C12H10F3N3O4.
It is freely soluble in ethyl acetate, acetone, chloroform, ethyl alcohol, dichloromethane, and methanol. It is slightly soluble in water [< 0.1% W/V at 25¡ãC (77¡ãF)]. It melts between 153¡ãC and 156¡ãC (307.4¡ãF and 312.8¡ãF).
Each NILANDRON tablet contains 150 mg of nilutamide. Other ingredients in NILANDRON tablets are corn starch, lactose, povidone, docusate sodium, magnesium stearate, and talc.
