DESCRIPTION
Timolol GFS (timolol maleate ophthalmic gel forming solution) is a non-selective beta-adrenergic receptor blocking agent.Its chemical name is (-)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol maleate (1:1) (salt).Timolol maleate possesses an asymmetric carbon atom in its structure and is provided as the levo-isomer.
The nominal optical rotation of timolol maleate is: [a]25º in 0.1N HCl (C=5%) = -12.2º.
405 nm
Its molecular formula is C13H24N4O3S¡¤C4H4O4 and its structual formula is:
Timolol maleate has a molecular weight of 432.50.It is a white, odorless, crystalline powder which is soluble in water, methanol, and alcohol.
