ULTRAVATE (halobetasol propionate cream) Cream contains halobetasol propionate, a synthetic corticosteroid for topical dermatological use. The corticosteroids constitute a class of primarily synthetic steroids used topically as an anti-inflammatory and anti-pruritic agent.

Chemically halobetasol propionate is 21-chloro-6α, 9-difluoro-11 ß -methylpregna-1, 4-diene-3-20-dione, 17-propionate, C₂₅H₃₁CIF₂O₅. It has the following structural formula:

Halobetasol propionate has the molecular weight of 485. It is a white crystalline powder insoluble in water.

Each gram of ULTRAVATE Cream contains 0.5 mg/g of halobetasol propionate in a cream base of cetyl alcohol, glycerin, isopropyl isostearate, isopropyl palmitate, steareth-21, diazolidinyl urea, methylchloroisothiazolinone, methylisothiazolinone and water.